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Photoreactors from Lab to Production

Photoreactor Designs

  • Tubular Flow Photoreactors (aka "Plug Flow Photoreactors")
  • Falling Film Photoreactors 
  • Side-loop Photoreactors
    • Side-loop Photoreactors 
    • Thin-film Side-loop Photoreactors
    • MISCOP Side-loop Photoreactors (static mixers)
    • Radial-flow Side-loop Photoreactors
  • Agitated Batch Photoreactors
    • Agitated Batch Photoreactors (low visocisty)
    • Scrape-mixed Batch Photoreactors (high viscosity)
    • Gas-dispersed Batch Photoreactors 
  • Flat Bed Photoreactors 
    • Thin Film Flow Photoreactors
    • Static Mixer Flow Photoreactors
    • Packed Bed Flow Photoreactors
    • Gas-liquid Flow Photoreactor
  • and more ...

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Typical Applications

  • Photochlorinations (e.g., Side-chain photochlorinations) 
  • Benzylic photobrominations for API intermediate synthesis
  • (Metalla)photoredox Cross-couplings
  • Steriod-hormone Synthesis (e.g., Vitamin D3 derivatives)
  • Vitmanin Production (e.g., Vitamin A) 
  • Rearangements (e.g., Norrish)
  • Isomerizations (e.g., Iribotecan by cis-trans isomerization)
  • Singlet-oxygen reactions (e.g., Artemisinin and rose oxide synthesis) 
  • Cycloadditions (e.g., oxetane intermediates via Paternò-Büchi reactions)
  • Cryogenic Photo-induced Fluorinations (e.g., Fomblin process)
  • Fluoroalkylations (e.g., Trilfuoromethylations with the Langlois reagent)
  • C-H Functionalizations

Best-available Photoreactor Technology for you Application?