Description

In collaboration with Peschl Ultraviolet GmbH, the tubular flow photoreactors use exchangeable FEP or glass tubes, mounted via a modular carrier design. These carriers are submerged in a temperature-controlled bath to safeguard excellent temperature regulation of the continuous-flow process. 

At the center of the carrier is a high-performance LED or a medium-pressure light source, with an independent, proprietary thermofluidic system for thermal decoupling of the lamp and flow reactor. 

The concentric profile ensures that the photons are effectively utilized in the process without significant reflection loss for both UV and visible light photochemistry applications.

The precise control of photochemical reactions in continuous flow improves the reliability throughout the reaction, combined with minimal hold up volume, making it making it the safest and best available solution for pharmaceutical and fine chemical applications. The excellent process control limits the formation of by-products otherwise caused by over-irradiation. 

Our photoFLOW reactors can be operated in different flow modes and scaled down to lower volumes for early development. The combination of the excellent temperature and process control makes photoFLOW the ideal solution for commercial-scale production.

Key Features

• Multipurpose Liquid Phase Photochemistry

• Mainly UV & Visible Ligh Direct Activations

• Complete Thermal Decoupling of Lamps (Proprietary)

• Exchangeable Tube Carriers (Variable Optical Path)

• Production Capacity for APIs & Fine Chemicals

Technical Specifications

Applications​

• Brominations for API intermediate synthesis
• Rearangements (e.g., Norrish)
• Isomerizations (e.g., Iribotecan by cis-trans isomerization)
• Singlet-oxygen reactions (e.g., Artemisinin and rose oxide synthesis) 
• Cycloadditions (e.g., oxetane intermediates via Paternò-Büchi reaction)

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